Pulmonary nocardiosisNocardiosis - pulmonary; Mycetoma; Nocardia
Pulmonary nocardiosis is an infection of the lung with the bacteria, Nocardia asteroides.
Nocardia infection develops when you breathe in (inhale) the bacteria. The infection causes pneumonia-like symptoms. The infection can spread to any part of the body.
People with a weak immune system are at a high risk for nocardia infection. This includes people who have:
- Been taking steroids or other medicines that weaken the immune system for a long time
- Cushing disease
- An organ transplant
Other people at risk include those with long-term (chronic) lung problems related to smoking, emphysema, or tuberculosis.
Pulmonary nocardiosis mainly affects the lungs. But, it can also spread to other organs in the body. Common symptoms may include:
- Fever (comes and goes)
- General ill feeling (malaise)
- Night sweats
- Liver and spleen swelling (hepatosplenomegaly)
- Loss of appetite
- Unintentional weight loss
LUNGS AND AIRWAYS
- Breathing difficulty
- Chest pain not due to heart problems
- Coughing up blood or mucus
- Rapid breathing
- Shortness of breath
MUSCLES AND JOINTS
- Change in mental state
- Changes in vision
Exams and Tests
Your health care provider will examine you and listen to your lungs using a stethoscope. You may have abnormal lung sounds, called crackles. Tests that may be done include:
The goal of treatment is to control the infection. Antibiotics are used, but it may take a while to get better. Your provider will tell you how long you need to take the medicines. This may be for up to a year.
Surgery may be needed to remove or drain infected areas.
Your provider may tell you to stop taking any medicines that weaken your immune system. Never stop taking any medicine before talking to your provider first.
The outcome is often good when the condition is diagnosed and treated quickly.
The outcome is poor when the infection:
- Spreads outside the lung.
- Treatment is delayed.
- The person has a serious disease that leads to or requires long-term suppression of the immune system.
Complications of pulmonary nocardiosis may include:
When to Contact a Medical Professional
Call your provider if you have symptoms of this disorder. Early diagnosis and treatment may improve the chance of a good outcome.
Be careful when using corticosteroids. Use these medicines sparingly, in the lowest effective doses and for the shortest periods of time possible.
Some people with a weak immune system may need to take antibiotics for long periods of time to prevent the infection from returning.
Southwick FS. Nocardiosis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 314.
Torres A, Menéndez R, Wunderink RG. Bacterial pneumonia and lung abscess. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 6th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 33.